The Indian Institute of Science (IISC) in Bangalore is developing a covid vaccine that can be kept at room temperature.
Experts believe that the initiative of IISC, a research institute in the country, is quite promising when there is a need to introduce more and more different types of covid vaccines in the market, while some foreign vaccines are awaiting government approval in India.
The researchers told that the main feature of this fancy covid vaccine is that it can be kept active at room temperature. The issue of temperature is still one of the only problems with Covid vaccines on the market. As a result, even if the temperature rises, it will not be difficult to move from one place to another with this vaccine. The refrigeration system does not need to be used to preserve this vaccine. As a result, there will be no risk of spoilage of the vaccine. The average room temperature in India is 21 to 25 degrees Celsius.
Raghavan Bardarajan, a professor at IISC, who is leading the vaccine project, said, "In a very short time. Those antibodies can easily inactivate the SARS-COV-2 virus that has entered rats and guinea pigs. The virus enters the cell and is no longer able to reproduce. As a result, there is no infection. "
These antibodies are called 'neutralizing antibodies' because they can inactivate the virus in cells.
"We've tested in infected human cells in test tubes in the laboratory, and the neutralizing antibodies that this vaccine is producing can even inactivate some new forms of the SARS-COV-2 virus," Bardarajan said.
Among those new strains of the SARS-COV-2 virus is the first mutated Indian mutant in Maharashtra, researchers claim.
Researchers at IISC have found that the amount of antibodies produced by convulsive plasma to prevent infection with the SARS-Curve-2 virus in human body cells is 200 times greater than the amount of antibodies produced by vaccines in rats.
"The main feature of our covid tick is that it can be kept at room temperature. As a result, there is no risk of the vaccine being spoiled at high temperatures. " says Raghavan.
The two indigenous covid vaccines now available in the Indian market, covacin and covishield, both need to be kept at a temperature of 2 to 8 degree Celsius to keep them active. Vaccines made by the American company Pfizer should be kept at a temperature below 60 degrees Celsius. Another American company, Moderna, also needs to be vaccinated at temperatures below 20 degrees Celsius. The Russian-made Sputnik V vaccine must be kept at a temperature of 2 to 6 degrees Celsius so that it does not spoil. This means that the vaccine made by IISC can be kept at about 3 times the temperature required to keep covacin, covishield or Sputnik V equally active.
What will be the efficacy of this vaccine in human body cells?
"To understand that, people need to be tested in at least two stages. We are awaiting approval for that trial. " says Raghavan.
